The manuscript contains notes from two separate courses of lectures given by Henry Clutterbuck (1770-1856); the first are on the practice of physic and cover ff.1-93, and the second are on the materia medica and cover ff.97-136.
Up to and including lecture 25 the practice of physic lectures are clearly marked and numbered, after this point there are only occasional attempts to mark the beginning of a new lecture. The contents are as follows: (0) Introductory lecture, (1) identification of and causes of disease, (2) disparity between symptoms and findings on dissection, and disease caused by disordered action, (3) varieties of disease, (4) of the pulse, (5) morbid state of the pulse, (6) pulse continued, (7) veins & absorption, (8) inflammation, (9) effects of inflammation, (10) of the general disorder occasioned by inflammation termed by Dr Cullen pyrexia [fever], (11-15) theory of inflammation, (16) treatment of inflammation including regimen, abstinence, and blood-letting, (17) blood-letting, counter irritation, purging, and cold, (18) counter irritation and narcotics, (19) treatment of specific inflammation, (20) theory of dropsy [oedema], (21) treatment of dropsy, (22) diseases of the nervous system, (23-24) physiology and diseases on the brain cont., (25) differing nature of the brain to other organs, inflammatory fever, malignant or putrid fever, and low nervous fever. The subjects covered in the rest of the lectures, in order, are as follows: of specific fevers-intermittents and remittents, detection of disease in early stages, of chronic affections of the brain - apoplexy [stroke], of paralysis, of epilepsy, of hysteria, of chorea, of tetanus, of mania, and books recommended by Clutterbuck, on diseases of the circulatory organs, diseased state of the heart, chronic carditis, blood vessels, diseases of veins, of diseases of the organs of respiration, the lungs, diseases of the air passages, catarrh, obstruction of air, of pleuritis [pleurisy], of pneumonia, of phthisis [tuberculosis, pulmonary], diseases of those organs whose office it is to supply the body with nutrients, odontalgia, tic douloureux [trigeminal neuralgia], diseases of the tongue, diseases of the salivary glands, diseases of the fauces, of the oesophagus, of the stomach, cholera morbus, of dysentery, of gastritis, of dyspepsia, of enteritis, colic, of worms, of haemorrhoids, of diseases of the liver, of calculi in the biliary ducts, of jaundice, and of the spleen.
The notes of lectures on the materia medica are clearly numbered throughout, with 10 in total. There contents are as follows: (1) introductory lecture, (2) operation and classification of medicines, (3-5) stimulants, (6) sedatives, (7) sedatives cont. and narcotics, (8) narcotics cont. and evacuants, (9) evacuants cont. and cathartics, (10) cathartics cont., diuretics, diaphoretics, and emmenagogues.