The inside front cover is signed 'Bellott Sept 1 1824' and it is possible that this could refer to Thomas Bellot (1806-1857) who came from a family of surgeons and was educated in Manchester. The manuscript contains notes on various medical subjects from a number of sources.
Folios 1-88 contain notes on ophthalmology with a contents page at the beginning dividing the contents into different chapters and sections. The subjects covered in these notes include: the conjunctiva (inflammation of the cornea, inflammation of the conjunctiva, pustular inflammation of the conjunctiva, inflammation of the follicles with purulent discharge, sclerotic conjunctiva in acute suppuration, mild suppuration, chemosis, carnosi fungi/fleshy fungi, pannus, pterygium, conjunctiva finis), cornea (vasa rubra cornea, acute interstitial ulcer, onyx and unguis [formation of matter between lamellae of the cornea], hypopyon, procidentia cornea, chronic interstitial ulcer, opacities, gangrene, cuticular conjunctiva, topical stimuli, opaque specks, staphyloma [pathologic dilation], conical cornea, finis), sclerotica (sclerotitis or rheumatic ophthalmia, staphyloma of the sclerotica, iritis, choroiditis, primary iritis, secondary iritis, terminations of iritis, mercurial iritis), retina (organic amaurosis [blindness], opacity of the retina, amaurosis from deep seated inflammation of the choroid or retina, amaurosis from various causes, sympathetic amaurosis, metastatic amaurosis, amaurosis from excitement, symptoms of amaurosis, amaurosis with cataract, ptosis [blepharoptosis], strabismus, hemiopsia [hemianopsia], ambiopsia), pathology of the humours (aqueous humours-hydrophthalmia, vitreous humour [vitreous body]-tremulous iris, discoloured vitreous humour, haemorrhoage of the vitreous humour, change of substance of the vitreous humours, crystalline humours-abscess of the capsule, opacity of the capsule, lenticular cataracts, formation of cataract), the eyeball (injuries, suppuration of the ball, fungus), orbitar appendages (abscess, tumour, hydatid [echinococcosis] tumour, aneurysm), facial appendages (hordeolum, lippitudo [blepharitis], tinea, tumours [neoplasms] of the palpebral, tumours of the eyelid, abscess of the upper lid, constricted puncta [lacrimal apparatus], stricture of the lachrymal conduit, abscess of the sac), and treatments of the various disorders of the eye. The final few pages are notes taken from the work of John Cunningham Saunders (1773-1810) and there are also references to William James Wilson (c.1792-1855) and John Vetch (1783-1835).
Following straight on from the ophthalmology notes are a series of notes on the following subjects: hernias taken from Grainger's work, circle of Willis and fracture of the patella from an unknown source, and dislocations of various joints from the work of Sir Astley Cooper (1768-1841). Folios 99-106 contain notes of four cases treated at the Manchester Royal Infirmary, for ulceration, dislocation of the elbow, injury to the shoulder after being struck by a sack of cotton, and variola [smallpox] as well as notes from a unknown source on gastric fever.
Folios 107-132 contain extracts from J.C. Saunders, Anatomy and Diseases of the Human Ear, 1817 and folios 133-212 are blank.
The notes towards the rear of the volume begin from the final folio and can be read when the volume is turned upside down. Folios 282-321 contain notes on subjects including luxations, dislocations, fractures, amputations, urinary calculus, imperforate anus, morbid inspections, and absorbents from a variety of sources making reference to a number of different physicians and surgeons including Astley Cooper (1768-1841), Bransby Cooper (1792-1853), Joseph Henry Green (1791-1863), John Armstrong (1784-1829), Charles Aston Key (1793-1849), and Benjamin Travers (1783-1858) as well as a cases seen at St Thomas's and Guy's Hospitals. Folios 224-281 are blank and notes on the absorbents by Green can be found on ff.213-223.